Everyone metabolizes all substances, including CBD oil, differently.
How a person responds to CBD oil can be partly influenced by genetic makeup, biological sex, lifestyle, and overall health.

These factors combined with the potency of your CBD oil supplement, how much CBD oil you consume and your method of consumption all play a role in how CBD will ‘make you feel’.
The typical starting dose for CBD is 15 mg once or twice daily and with any medication, it is always best to start low and go slow. 

*Taking CBD on a full stomach allows more CBD to reach the circulatory system and faster. Some suggest taking CBD with Omega-3 ensures maximum potential benefit. 

 * On average the effects of CBD oil last 3-5 hours. 

Drug Interactions

p>CBD interacts with the Cytochrome P450 enzyme system in the liver and could potentially prevent other drugs from accessing these enzymes, causing some of them to build up in the bloodstream affecting potency. It is unknown how long any given dose of CBD would exert an effect.

This enzyme system is involved in processing about 60% of all pharmaceuticals on the market, including common psych drugs like Klonopin, Valium, Xanax, and a long list of antihistamines, antiretrovirals, and steroids, to name a few.
Anyone taking significant doses of CBD and other drugs simultaneously should be cautious. People on chemotherapy drugs and warfarin blood thinners should be on alert given how easily an increased blood concentration of either could lead to serious negative side effects.
If you have blood pressure issues, are taking prescription drugs or have ever been warned about ingesting fruit juice, citrus or fermented products, consult your doctor before using CBD oil.

A report from the American Academy of Pediatrics (AAP) published in the journal Pediatrics cautions pregnant women and nursing mothers to avoid marijuana use due to possible adverse developmental effects on their baby. In a study reviewed for the report, short-term exposure to CBD was found to increase the permeability of the placental barrier, potentially placing the fetus at risk from certain substances.

It is also important to note that hemp has been used medicinally for thousands of years and considered by many to be safe and benign.
Studies are needed. There is currently a lack of information and very little fair balance information for those using CBD as an alternative to pharmaceuticals.

Safety is knowing exactly what is in the CBD product you are using.

Side Effects

According to a report by the World Health Organization CBD exhibits no effects indicative of any abuse or dependence potential.
There is no evidence at the moment that CBD oil tends to be either physically or psychologically habit-forming.

Small-scale studies have looked into the safety of CBD in adults and concluded that adults tend to tolerate a wide range of doses well. Researchers have found no significant side effects on the central nervous system, vital signs, or mood, even among people who used high dosages.

Some patients reported diarrhea and changes in appetite or weight. The most common side effect was tiredness..

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